When to use #define:

1. When you’re declaring macros like in Apple’s:

   #define UI_USER_INTERFACE_IDIOM() ([[UIDevice currentDevice] respondsToSelector:@selector(userInterfaceIdiom)] ? [[UIDevice currentDevice] userInterfaceIdiom] : UIUserInterfaceIdiomPhone) 
   

I’m actually not even sure why this wasn’t made as a function like NSLog instead of a macro.

When not to use #define:

1. When you’re declaring constants. Constants should look like:

   NSString *const RWSSomeConstantName = @"theValueDoesn'tUsuallyMatter";
   const NSInteger RWSIntegerConstant = 3;
   

Why go through this effort to type extra letters?

1. Constants declared using #define don’t show up in tools like the debugger. #define is raw text substitution, constants are symbols to your debugger, like class names.
2. #define won’t warn you if you use #define in some other file and change the value of your constant accidentally.